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(2019) ‘C9orf72 expansion within astrocytes reduces metabolic flexibility in amyotrophic lateral sclerosis’ - 'Brain', 142 (12), pp. 3771–3790. doi: 10.1093/brain/awz302. Bennison, D. J., Irving, S. E. and Corrigan, R. M. (2019) ‘The Impact of the Stringent Response on TRAFAC GTPases and Prokaryotic Ribosome Assembly’ - 'Cells, 8'(11), p. 1313. doi: 10.3390/cells8111313. da Silva, B., Irving, B. K., Polson, E. S., Droop, A., Griffiths, H. B. S., Mathew, R. K., Stead, L. F., Marrison, J., Williams, C., Williams, J., Short, S. C., Scarcia, M., O’Toole, P. J., Allison, S. J., Mavria, G. and Wurdak, H. (2019) ‘Chemically induced neurite-like outgrowth reveals a multicellular network function in patient-derived glioblastoma cells’ - 'Journal of Cell Science, 132'(19). doi: 10.1242/jcs.228452. Devlin, L. A. and Sayer, J. A. ‘Renal ciliopathies’, Current Opinion in Genetics & Development. (Molecular and genetic basis of disease), 56, pp. 49–60. doi: 10.1016/j.gde.2019.07.005. Duncan, C. J. A., Thompson, B. J., Chen, R., Rice, G. I., Gothe, F., Young, D. F., Lovell, S. C., Shuttleworth, V. G., Brocklebank, V., Corner, B., Skelton, A. J., Bondet, V., Coxhead, J., Duffy, D., Fourrage, C., Livingston, J. H., Pavaine, J., Cheesman, E., Bitetti, S., Grainger, A., Acres, M., Innes, B. A., Mikulasova, A., Sun, R., Hussain, R., Wright, R., Wynn, R., Zarhrate, M., Zeef, L. A. H., Wood, K., Hughes, S. M., Harris, C. L., Engelhardt, K. R., Crow, Y. J., Randall, R. E., Kavanagh, D., Hambleton, S. and Briggs, T. A. (2019) ‘Severe type I interferonopathy and unrestrained interferon signaling due to a homozygous germline mutation in STAT2’ - 'Science Immunology' doi: 10.1126/sciimmunol.aav7501. Duncan, J. A., Foster, R. and Kwok, J. C. F. (2019) ‘The potential of memory enhancement through modulation of perineuronal nets’ - 'British Journal of Pharmacology' 176(18), pp. 3611–3621. doi: 10.1111/bph.14672. Hatton, C. F. and Duncan, C. J. A. (2019) ‘Microglia Are Essential to Protective Antiviral Immunity: Lessons From Mouse Models of Viral Encephalitis’ - 'Frontiers in Immunology' doi: 10.3389/fimmu.2019.02656. Mallett G, Laurence A and Amarnath S (2019) 'Programmed Cell Death-1 Receptor (PD-1)-Mediated Regulation of Innate Lymphoid cells' - 'International Journal of Molecular Sciences' doi: 10.3390/ijms20112836 Manners, O., Baquero-Perez, B. and Whitehouse, A. (2019) ‘m6A: Widespread regulatory control in virus replication’, Biochimica et Biophysica Acta (BBA)' - 'Gene Regulatory Mechanisms. (mRNA modifications in gene expression control)', 1862(3), pp. 370–381. doi: 10.1016/j.bbagrm.2018.10.015. Masi A.C., Stewart C.J. (2019) ‘The role of the preterm intestinal microbiome in sepsis and necrotising enterocolitis’ - 'Early Hum Dev' doi: 10.1016/j.earlhumdev.2019.104854 Miles, J., Scherz-Shouval, R. and van Oosten-Hawle, P. (2019) ‘Expanding the Organismal Proteostasis Network: Linking Systemic Stress Signaling with the Innate Immune Response’ - 'Trends in Biochemical Sciences' doi: 10.1016/j.tibs.2019.06.009. Molinari, E., Ramsbottom, S. A., Srivastava, S., Booth, P., Alkanderi, S., McLafferty, S. M., Devlin, L. A., White, K., Gunay-Aygun, M., Miles, C. G. and Sayer, J. A. (2019) ‘Targeted exon skipping rescues ciliary protein composition defects in Joubert syndrome patient fibroblasts’ - 'Scientific Reports' doi: 10.1038/s41598-019-47243-z. Powell, L., Samarakoon, Y. H., Ismail, S. and Sayer, J. A. (2019) ‘ARL3, a small GTPase with a functionally conserved role in primary cilia and immune synapses’, Small GTPases, 0(0), pp. 1–10. doi: 10.1080/21541248.2019.1703466. Ramsbottom, S. A., Thelwall, P. E., Wood, K. M., Clowry, G. J., Devlin, L. A., Silbermann, F., Spiewak, H. L., Shril, S., Molinari, E., Hildebrandt, F., Gunay-Aygun, M., Saunier, S., Cordell, H. J., Sayer, J. A. and Miles, C. G. 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Urszula L McClurg, Arash Nabbi, Charles Ricordel, Svitlana Korolchuk, Stuart McCracken, Rakesh Heer, Laura Wilson, Lisa M Butler, Bronwyn Kate Irving-Hooper, Rémy Pedeux, Craig N Robson, Karl T Riabowol & Olivier Binda Human ex vivo prostate tissue model system identifies ING3 as an oncoprotein – ‘British Journal of Cancer’ doi:10.1038/bjc.2017.447 Adamson, K. I., Sheridan, E. and Grierson, A. J. (2018) ‘Use of zebrafish models to investigate rare human disease’, Journal of Medical Genetics, 55(10), pp. 641–649. doi: 10.1136/jmedgenet-2018-105358. Bansagi, B., Phan, V., Baker, M. R., O’sullivan, J., Jennings, M. J., Whittaker, R. G., Müller, J. S., Duff, J., Griffin, H. and Miller, J. A. (2018) ‘Multifocal demyelinating motor neuropathy and hamartoma syndrome associated with a de novo PTEN mutation’, Neurology, 90(21), pp. e1842–e1848. doi: 10.1212/WNL.0000000000005566. Bartoli, F., Bailey, M., Rode, B., Mateo, P., Gosain, R., Plante, J., Norman, K., Gomez, S., Lefebvre, F., Rucker-Martin, C., Gomez, A. M., Beech, D., Foster, R., Benitah, J. P. and Sabourin, J. (2018) ‘Orai1 channels inhibition protects the heart from pressure overload-induced ventricular dysfunction’, Journal of Molecular and Cellular Cardiology. (SI:Abstracts ISHR-ES Amsterdam), 120, p. 12. doi: 10.1016/j.yjmcc.2018.05.046. Boczonadi, V., Jennings, M. J. and Horvath, R. (2018) ‘The role of tRNA synthetases in neurological and neuromuscular disorders’, FEBS Letters, 592(5), pp. 703–717. doi: 10.1002/1873-3468.12962. Juneja, M., Azmi, A., Baets, J., Roos, A., Jennings, M. J., Saveri, P., Pisciotta, C., Bernard-Marissal, N., Schneider, B. L., Verfaillie, C., Chrast, R., Seeman, P., Hahn, A. F., Jonghe, P. de, Maudsley, S., Horvath, R., Pareyson, D. and Timmerman, V. (2018) ‘PFN2 and GAMT as common molecular determinants of axonal Charcot-Marie-Tooth disease’, Journal of Neurology, Neurosurgery & Psychiatry, 89(8), pp. 870–878. doi: 10.1136/jnnp-2017-317562. Manners, O., Murphy, J. C., Coleman, A., Hughes, D. J. and Whitehouse, A. (2018)‘Contribution of the KSHV and EBV lytic cycles to tumourigenesis’, Current Opinion in Virology. (Engineering for viral resistance - Viruses and cancer), 32, pp. 60–70. doi: 10.1016/j.coviro.2018.08.014. Muniyandi, S., Pangratiou, G., Edwards, T. A. and Barr, J. N. (2018) ‘Structure and Function of the Human Respiratory Syncytial Virus M2–1 Protein’, in Harris, J. R. and Bhella, D. (eds) Virus Protein and Nucleoprotein Complexes. Singapore: Springer (Subcellular Biochemistry), pp. 245–260. doi: 10.1007/978-981-10-8456-0_11. Peffers, M. J., Balaskas, P. and Smagul, A. (2018) ‘Osteoarthritis year in review 2017: genetics and epigenetics’, Osteoarthritis and Cartilage, 26(3), pp. 304–311. doi: 10.1016/j.joca.2017.09.009. Ramsbottom, S. A., Molinari, E., Srivastava, S., Silberman, F., Henry, C., Alkanderi, S., Devlin, L. A., White, K., Steel, D. H., Saunier, S., Miles, C. G. and Sayer, J. A. (2018) ‘Targeted exon skipping of a CEP290 mutation rescues Joubert syndrome phenotypes in vitro and in a murine model’, Proceedings of the National Academy of Sciences, 115(49), pp. 12489–12494. doi: 10.1073/pnas.1809432115. Rubaiy, H. N., Ludlow, M. J., Siems, K., Norman, K., Foster, R., Wolf, D., Beutler, J. A. and Beech, D. J. (2018) ‘Tonantzitlolone is a nanomolar potency activator of transient receptor potential canonical 1/4/5 channels’, British Journal of Pharmacology, 175(16), pp. 3361–3368. doi: 10.1111/bph.14379. Selvaraj, M., Yegambaram, K., Todd, E. J. A. A., Richard, C.-A., Dods, R. L., Pangratiou, G. M., Trinh, C. H., Moul, S. L., Murphy, J. C., Mankouri, J., Éléouët, J.-F., Barr, J. N. and Edwards, T. A. (2018) ‘The Structure of the Human Respiratory Syncytial Virus M2-1 Protein Bound to the Interaction Domain of the Phosphoprotein P Defines the Orientation of the Complex’, mBio, 9(6). doi: 10.1128/mBio.01554-18. Stathopoulou C, Gangaplara A, Mallett G, Flomerfelt F A, Liniany L P, Knight D, Samsel L A, Berlinguer-Palmini R, Yim J J , Felizardo T C, Eckhaus M A, Edgington-Mitchell L, Martinez-Fabregas J, Zhu J, Fowler D H, Van Kasteren S I, Laurence A, Bogyo M, Watts C, Shevach E M and Amarnath S (2018) 'PD-1 Inhibitory Receptor Downregulates Asparaginyl Endopeptidase and Maintains Foxp3 Transcription Factor Stability in Induced Regulatory T cells' Immunity 49 (2) 247-263 ; doi: 10.1016/j.immuni.2018.05.006 ​

Allen, C. F., Shaw, P. J. and Ferraiuolo, L. (2017) ‘Can Astrocytes Be a Target for Precision Medicine?’, in El-Khamisy, S. (ed.) Personalised Medicine: Lessons from Neurodegeneration to Cancer. Cham: Springer International Publishing (Advances in Experimental Medicine and Biology), pp. 111–128. doi: 10.1007/978-3-319-60733-7_7. Balaskas, P., Goljanek-Whysall, K., Clegg, P., Fang, Y., Cremers, A., Emans, P., Welting, T. and Peffers, M. (2017) 'MicroRNA Profiling in Cartilage Ageing', International Journal of Genomics. doi: 10.1155/2017/2713725. Feng, S., Bowden, N., Fragiadaki, M., Souilhol, C., Hsiao, S., Mahmoud, M., Allen, S., Pirri, D., Ayllon Tardajos, B., Akhtar, S., Thompson, A. A. R., Jo, H., Weber, C., Ridger, V., Schober, A. and Evans, P. C. (2017) ‘Mechanical Activation of Hypoxia-Inducible Factor 1α Drives Endothelial Dysfunction at Atheroprone Sites’, Arteriosclerosis, Thrombosis, and Vascular Biology, 37(11), pp. 2087–2101. doi: 10.1161/ATVBAHA.117.309249. Marsh, S. A., Arthur, H. M. and Spyridopoulos, I. (2017) ‘The secret life of nonclassical monocytes’, Cytometry Part A, 91(11), pp. 1055–1058. doi: https://doi.org/10.1002/cyto.a.23280 Gleeson, P. J., Wilson, V., Cox, T. E., Sharma, S. D., Smith-Jackson, K., Strain, L., Lappin, D., McHale, T., Kavanagh, D. and Goodship, T. H. J. (2016) ‘Chromosomal rearrangement—A rare cause of complement factor I associated atypical haemolytic uraemic syndrome’, Immunobiology. (SI: XXVI ICW Kanazawa 2016), 221(10), pp. 1124–1130. doi: 10.1016/j.imbio.2016.05.002. Lawrence, H., Deehan, D. J., Holland, J. P., Anjum, S. A., Mawdesley, A. E., Kirby, J. A. and Tyson-Capper, A. J. (2016) ‘Cobalt ions recruit inflammatory cells in vitro through human Toll-like receptor 4’, Biochemistry and Biophysics Reports, 7, pp. 374–378. doi: 10.1016/j.bbrep.2016.07.003. Lawrence, H., Mawdesley, A. E., Holland, J. P., Kirby, J. A., Deehan, D. J. and Tyson-Capper, A. J. (2016) ‘Targeting Toll-like receptor 4 prevents cobalt-mediated inflammation’, Oncotarget, 7(7), pp. 7578–7585. doi: 10.18632/oncotarget.7105.

iCASE_2025_01: Precision Diabetic Medicine: Using the lipidome to optimize exercise as a therapeutic strategy in the ageing diabetes patient (Prof Lee Roberts) iCASE_2025_12: Novel multi-ion therapeutics to reverse early dental caries and improve oral health (Prof Maisoon Al-Jawad) iCASE_2025_09: Applying cutting-edge machine learning to rectal cancer MRI from a tertiary hospital: predicting treatment effect for chemoradiotherapy and immunotherapy (Dr Samuel Relton) iCASE_2025_25: The devil is in the details: exploiting biased receptor signalling to instruct development of precision oncology drugs (Dr Natalia A. Riobo-Del Galdo) Standard_2025_161: Identification of cellular receptors for bunyaviruses, a group of emerging haemorrhagic fever viruses (Dr John Barr) Standard_2025_189: Seeing inside the Parkinson’s disease brain by in situ cryo-ET (Dr Rene Frank) Standard_2025_147: Developing Small-Molecule Therapeutics for Recurrent, Therapy-Resistant Brain Cancer (Dr Robin Bon) Standard_2025_207: Developing the next generation of glycopeptide antibiotics (Dr Ryan Seipke) Standard_2025_121: Multiplexed infection biomarker detection with a single molecule biosensor (Prof Christoph Wälti) Standard_2025_139: Biological mechanisms underlying the frailest of patients with peripheral arterial disease (Dr Scott Bowen) Standard_2025_157: Revealing the molecular basis for differences in radiotherapy response and survival in HPV positive and HPV negative anal cancers (Prof Andrew MacDonald) Standard_2025_155: Modulation of neural extracellular matrix to improve frailty during ageing (Dr Jessica Kwok) Standard_2025_216: Uncovering the function of novel, neuronal, long non-coding RNA derived, micropeptides and their contribution to brain cancers (Dr Julie Aspden) Standard_2025_184: Using AI to predict amyloid aggregation in neurodegenerative diseases (Prof David Brockwell) Standard_2025_148: Primary Cilia Manipulation to Combat Systemic Fibrosis (Dr Rebecca Ross) Standard_2025_63: Understanding how phytochemicals exert anti-cancer effects with chemical proteomics (Dr James Thorne) Standard_2025_130: Investigating α-synuclein aggregation in microglia using human microglia transplanted into the mouse brain and cryo-electron microscopy (Dr Marine Krzisch) Standard_2025_166: Establishing the link between extracellular vesicles, maternal cardiac dysfunction and offspring cardiovascular health in pregnancies complicated by maternal diabetes (Dr Karen Forbes)

Standard_2025_158: Migration of Pseudomonas aeruginosa towards antibiotics: mechanisms and consequences (Dr Jamie Wheeler) iCASE_2025_07: Characterization of immunological responses in patients with liver cancer to predict immunotherapy efficacy and immune-related adverse events (Dr Xiaoli Meng) iCASE_2025_23: Exploring the anti-fibrotic activity and underlying molecular mechanisms of targeted compounds in patient derived models of Dupuytren’ disease and cancer (Dr Elizabeth Laird) iCASE_2025_10: Role of phosphodiesterases (PDEs) in atrial IP3 signaling and exploring the potential of utilizing them as therapies for atrial fibrillation (Dr Rebecca Burton) Standard_2025_195: Regulation of transcription replication conflicts in ca ncer: mechanism and functional implications in acute myeloid leukemia. (Dr Manolis Papamichos Chronakis) Standard_2025_58: Development of a biocompatible and bioabsorbable auxetic metamaterial for bone fixation (Dr Rosti Readioff) Standard_2025_205: Identification of Accessible Biomarkers Reflecting NRF2 Modulation in Humans (Prof Ian Copple) Standard_2025_45: Understanding how diabetes affects retinal cell crosstalk (Prof Reinhold Medina) Standard_2025_64: Decoding Shank3: New Insights into neuronal maintenance and neurodegeneration via structural analysis and Drosophila models (Dr Igor Barsukov) Standard_2025_208: Signalling systems in Pseudomonas: understanding new routes to prevent Pseudomonas aeruginosa adaptation (Prof Jo Fothergill) Standard_2025_99: Mitochondrial quality control for a healthy brain (Prof Michael Clague) Standard_2025_26: Cracking the Mitochondrial Code: New Frontiers in Tackling Linezolid Toxicity for Multi-Drug Resistant Tuberculosis (Dr Amy Chadwick) Standard_2025_60: Dissecting diversity of complement component 8-binding cell surface proteins to enhance leptospiral vaccine efficacy (Prof Nicholas Evans) iCASE_2025_16: Cardiovascular function around the clock: harnessing protective circadian mechanisms towards smarter design of novel retinoid therapies and lifestyle interventions (Dr Vanja Pekovic-Vaughan) iCASE_2025_17: Therapeutics for Middle Eastern Respiratory Syndrome (Prof James Stewart) iCASE_2025_02: A novel theragnostic approach for treating brain tumours (Prof Harish Poptani) Standard_2025_193: Bioengineering a protein nanocage as a novel drug and antigen vaccine delivery nanoplatform for cancer therapeutics (Prof Luning Liu) Standard_2025_153: Understanding skeletal tissue responses to sex and menopause in osteoarthritis (Dr Blandine Poulet) Standard_2025_127: Understanding the mechanisms of norovirus replication (Dr Edward Emmot) Standard_2025_163: Ageing-related susceptibility to pneumococcal pneumonia (Prof Aras Kadioglu) Standard_2025_219: The Biting-Edge of AI – Predicting Mosquito Vector Competence for Arboviruses (Dr Marcus Blagrove) Standard_2025_25: Uncovering the molecular mechanisms underpinning A. baumannii virulence (Dr Christopher Harding) Standard_2025_56: Un veiling novel interactions between the human complement system and pathogenic Neisseria (Dr Hayley Lavender) Standard_2025_71: Widening the ‘NET’ to identify new treatments for bronchiectasis (Dr Helen Wright)

iCASE_2025_15: Improving risk-directed treatment stratification for patients with rarer cancers (Dr Sarra Ryan) iCASE_2025_21: Chemical and structural biology tools to mimic frataxin function in iron-sulphur cluster biosynthesis (Prof Wyatt Yue) iCASE_2025_26: Investigating how ageing and anti-fungal resistance affect host-pathogen interactions in a C. elegans model of fungal infection (Dr Elizabeth Veal) Standard_2025_50: Unlocking the tumour glyco-code to transform the diagnosis and treatment of breast and prostate cancer (Dr Jennifer Munkley) Standard_2025_136: Unravelling how human milk bioactive components modulate the infant gut microbiome (Prof Christopher Stewart) Standard_2025_79: Investigating the role of novel motor protein in tendon development and aging (Dr Katarzyna Pirog) Standard_2025_91: In vivo modelling to develop novel therapies against neurocognitive deficits in childhood cancer survivors (Dr Debbie Hicks) Standard_2025_173: Metabolic barcoding of microbial antibiotic exposomes (Dr Katherine Duncan) Standard_2025_105: Macrophage reprogramming in response to the clearance of pathogen-induced cell death (Prof Matthias Trost) Standard_2025_59: Mitonuclear Genetic Interactions and disease: From genetic predisposition to disease mechanisms (Dr Gavin Hudson) Standard_2025_16: Collagen modifying enzyme COLGALT2 as a mediator of osteoarthritis risk (Dr Sarah Rice) Standard_2025_179: Biomarker-driven risk-stratification of childhood medulloblastoma for improved therapies (Dr Stacey Richardson) Standard_2025_138: The role of nuclear proximity in mitochondrial genetics (Dr Amy Vincent) Standard_2025_78: Investigating regulatory role of transposable elements in human retina during development and aging (Dr Rachel Queen) Standard_2025_108: Discovery of resistance-breaking antibiotics targeting bacterial lipids (Prof Henrik Strahl) Standard_2025_135: Targeting the cytoplasmic regulators of androgen receptor signalling in prostate cancer (Dr Kelly Coffey) Standard_2025_111: Deciphering the impact of DNA damage repair on Staphylococcal infections (Dr Charles Winterhalter) Standard_2025_66: Development of an in vitro co-culture model for the study of upper airway immunity (Dr Jason Powell)

iCASE_2025_11: Synthetic UTRs for mRNA therapeutics (Dr Ian Sudbery) iCASE_2025_27: Understanding how damaged DNA is excised and repaired to maintain genome integrity and prevent cancer (Dr Matthew Newton) iCASE_2025_20: Developing Novel Anti-Inflammatory Agents for Age-Related Diseases (Dr Heather Wilson) Standard_2025_124: Tools to reduce surgical infection: Developing a 3D tissue engineered model of surgical infection and optimisation of skin-facing antimicrobial surgical devices produced through Additive Manufacturing (Joanna Shepherd) Standard_2025_29: Understanding the membrane recruitment of oncogenic KRAS in pancreatic cancer (Dr Helen Matthews) Standard_2025_08: Can frailty be prevented? (Prof Ilaria Bellantuono) Standard_2025_23: Understanding the mechanisms associated with mitochondria dysfunction underpinning both age-related hearing loss and neurodegenerative diseases (Prof Walter Marcotti) Standard_2025_19: Getting to the heart of cardiac infection using zebrafish models (Dr Philip Elks) Standard_2025_36: Digital outcome measures, functional imaging and molecular analysis to mechanistically stratify patients with Parkinson's disease (Prof Oliver Bandmann) Standard_2025_137: Targeting neural–stromal crosstalk in cancer (Prof Fiona Boissonade) Standard_2025_118: Developing new modes of anti-cancer drug delivery using tissue engineered cancer and mass spectrometry imaging (Prof Craig Murdoch) Standard_2025_170: Breaking the wall to finding new drugs for antimicrobial resistant fungi (Dr Simon Johnston) Standard_2025_04: Examining the role of metabolism in paediatric cancer initiation using human pluripotent stem cells (Dr Anestis Tsakiridis) Standard_2025_37: Why do multiple pathogenic viruses including HIV, Influenza, Ebola, Herpesviruses and Adenovirus target a host RNA binding protein? (Prof Stuart Wilson) Standard_2025_80: The Role of Social Isolation and Loneliness in Dementia: Natural Language Processing of Patients’ Electronic Health Records (Dr Nemanja Vaci) Standard_2025_11: A bioelectrical approach to control breast cancer invasion (Dr Alexander Fletcher) Standard_2025_145: A search for pharmacological inhibitors of a cancer-associated adhesion GPCR in the zebrafish embryo (Prof Tanya Whitfield) Standard_2025_200: Tackling ageing in the gut: investigating the contribution of macrophages in the intestinal stem cell niche to gut maintenance and repair (Dr Catarina Henriques) Standard_2025_202: Old-age macrophages? Programming distinct immune behaviours across the lifecourse (Dr Iwan Evans)

iCASE_2025_05: Magnetic Nanoparticles with Elastin-Like Peptide Coating for Delivery of Therapeutic Proteins for Bone Disease Treatment (Prof Victor Chechik) iCASE_2025_19: Nano-drug delivery systems from engineered stem cells (Prof Paul Genever) iCASE_2025_24: Enhancing LNP-RNA delivery to leukemia cells through cutting-edge cryogenic electron tomography (Dr Jamie Blaza) iCASE_2025_30: Exploring cancer transcriptomes with Nanopore long-read sequencing (Prof Dimitris Lagos). Standard_2025_47: Investigating the role and regulation of biomolecular condensate enabling trypanosome parasites host adaptation (Dr Mathieu Cayla) Standard_2025_86: Divide and Conquer: Unravelling how blood cancers take over using state-of-the-art technologies. (Prof David Kent) Standard_2025_164: Understanding cellular mechanisms underlying the autism spectrum disorder Neurofibromatosis type 2 (Dr Ines Hahn) Standard_2025_10: Engineering mosquitoes to provide no-cold-chain delivery of vaccines (Prof Luke Alphey) Standard_2025_102: Skin inflammatory disorders modulate susceptibility to virus infection (Dr Clive McKimmie) Standard_2025_174: Optical methods for biomarker discovery in prostate cancer—cells to circulating cellular components (Dr Yvette Hancock) Standard_2025_95: The impact of a wild lifestyle on age-related immune dysfunction (Dr James Hewitson) Standard_2025_42: Discovering immunoregulatory pathways used by pathogens to identify new immunotherapeutic targets for cancer and autoimmune disease (Prof Gavin Wright) Standard_2025_18: Exploration of Ruthenium Complexes as Potential Candidates against Mycobacteria (Dr Angelo Frei) Standard_2025_98: Investigating attached Leishmania forms and their contribution to human infections (Dr Nicola Baker) Standard_2025_160: The wrong place at the wrong time? The role of TMEM106b trafficking in dementia (Dr Noemie Hamilton) Standard_2025_128: Masters of disguise: Illuminating the regulatory role of SUMOylation in Trypanosome immune evasion (Dr Joana Faria) Standard_2025_67: GAGs, CCL5 and CCR5: elucidating a complex partnership for cancer immunotherapy (Dr Nathalie Signoret) Standard_2025_68: Identifying and imaging pathology in Parkinson’s Disease at cellular, neuronal circuit and behavioural levels (Prof Sean Sweeney) Standard_2025_69: Characterisation of the molecular pathway underlying RNA-binding deficient TDP-43 in neurodegeneration (Dr Han-Jou Chen) Standard_2025_213: Understanding molecular mechanisms of protein-primed genome replication in enteroviruses (Dr Chris Hill)

Yes you must apply to three projects. We recommend you contact the supervisors before submitting your application to discuss their research in more detail and inform your decision. If you are shortlisted to the interview stage, you will be asked to rank projects in order of preference. Not all candidates are offered their first choice of project and you may be offered your second or third choice.

No, you can apply for any combination of 3 projects, regardless of the institution at which these are based.

Yes. You should apply to DiMeN with only one application form - select three projects from the dropdown tool.

Applicants need to meet the English language condition of their offer by the deadline for meeting all offer conditions, which is the 8th September 2025 for applicants that will need to apply for CAS: https://www.sheffield.ac.uk/postgraduate/deadlines

Many of our applicants are studying for an Undergraduate or Masters qualification which is still in progress. Applicants need to meet the condition of their offer by 8th September 2025.

References are not viewed during the shortlisting process. However, if you are selected for interview your references and CV will be made available to your project supervisors and interview panel as part of the selection process. The deadline for uploading references is 25th January 2025.

We will be holding interviews online between 24th and 28th February 2025 and aim to contact shortlisted candidates by 3rd February. We typically receive over 700 applications to DiMeN and therefore it can take some time for non-shortlisted candidates to receive an individual formal rejection. However, we will post more general updates on the DiMeN website during the selection process so please check for new information.

If you are having issues try switching to a different browser such as Chrome. The application portal is managed by the University of Sheffield - please contact our admission team using the chat function on the prospective students page with any queries.

Some projects are feasible part-time, however not all of them due to the specific experimental work commitments and you would need to discuss this as an option with the supervisory team before applying. International students must also consider UK Visas and Immigration (UKVI) restrictions and contact the host university international office for advice. Part-time study can only be at 50% of full time, so our 4 year programme would be spread over 8 years and stipend funding at 50% per payment. This has implications on Council tax as part-time students are no longer exempt. It is possible to switch to part-time during your PhD according to personal circumstances and this is reviewed locally, on a case-by-case basis.

We accept applications from international students, however there is a 30% cap on places for international students on our programme. Fees are covered for international fee status students but candidates are required to meet all visa, healthcare surcharges, and relocation costs. You can find out more about fee status here.